Product Name :
Clinical Significance :
Apo A1 is the major protein component of HDL. Apo A1 activates lecithin cholesterol acyltransferase which catalyses the esterification of cholesterol. This esterified cholesterol can then be transported to the liver, metabol ized and excreted. In people with atherosclerotic vascular changes frequently exhibit decreased levels of Apo A1. Decreased APO A1 is a risk factor for artherosclerosis even in normal APO B concentrations. Apo A1 decreases also seen in dyslipoproteinemias, acute hepatic cirrhosis and insulin treated patients.
Intended Use :
This reagent is intended for in vitro quantitative determination of Apo A1 in human serum .
-Linear up to 300 mg/dL
-Ready to use reagents
-No calibration required
-Lower detection level 15 mg/dL