Product Name :
Apo B
Company :
Intended Use
This reagent is intended for in vitro quantitative determination of Apo B in human serum .-Nephelometry methodology
-Linear up to 330 mg/dL
-Ready to use reagents
-No calibration required
-Lower detection level 20 mg/dL
Clinical Significance
Apo B1 is the major protein component of LDL. It is necessary for the reaction of LDL with receptors in the liver and cel l walls and thus involved in transporting cholesterol from the liver to the vessel cells. Elevated levels of Apo B is frequently found in atherosclerotic vascular changes and are risk factor for atherosclerosis.
Principle
The reagents containing anti-human Apo B antisera when mixed with serum sample containing Apo-B1 cause changes in absorbance, due to the development of Immune complex, which is directly proportional to the concentration of Apo-B1 in the sample.
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