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Intended Use

This reagent is used for in vitro quantitative determination of fibrin degradation product D-dimer in human plasma by Nephelometric Immunoassay.
Nephelometry methodology Linear up to 10 µg/mL Ready to use reagents
No calibration required

Clinical Significance

FDPS (Fibrin and Fibrinogen Degradation Products) are generic name for several degradation products formed as the result of plasmin med iated proteolytic degradation of fibrin and fibrinogen. FDP assay become important test to diagnose or monitor fobrinolytic disorder, especial ly disseminated intravascular coagulation (DIC). But FDP assay also detects the degradation products of fibrinogenolysis.

D-dimer assay is more specific for fibrinolysis because it can only be produced as the result of plasma mediated, proteolytic degradation of fibrin.


This D-dimer assay is a nephelometric assay that utilizes antibody coated latex particles. In the presence of D-dimer, the particles aggregate and light scattering increases. The increase in scattering is proportional to the amount of D-dimer in sample.

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